Researchers find 1,200 genetic variants tied to personality in study of over a million people

Scientists at the University of Bristol identified about 1,200 genetic variants associated with the Big Five personality traits in a study of more than one million people, published September 2 in Nature. The traits are extroversion, agreeableness, conscientiousness, neuroticism and openness to experience. Common genetic variants account for a small percentage of variation in these traits within a population, but the associations proved more robust to confounding factors such as family background than genetic links to education level or income. The team connected personality genetics to health and lifestyle outcomes, including smoking behavior, COVID-19 infection risk and participation in research studies.
Researchers can now use the genome to study how personality influences health and behavior across populations. This genetic tool has lagged behind studies of other behavioral traits.
Written by the Genomes desk from the primary source cited and linked above and checked against it. Research use only; not medical advice. Corrections: [email protected].