New Protocol Details How to Find Neanderthal and Denisovan DNA in Living Humans
Zhou and Browning from the University of Washington published a protocol for using the SPrime program to identify genetic variants introgressed from Neanderthals and Denisovans in present-day human populations. The method was applied to 1000 Genomes Project data, focusing on the Han Chinese in Beijing population. The protocol appeared in STAR Protocols and builds on methods described in Browning et al. (2018). SPrime is optimized for detecting introgression from Neanderthals and Denisovans in modern humans.
The protocol enables researchers to trace archaic ancestry in living populations and study human evolutionary history.
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